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The Ludus helmontii and the stone disease
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"Our archival researches at the Royal Society reveal that a small envelope attached to a 1675 letter from an Antwerp apothecary, A. Boutens, contained a sample of the ‘Ludus’ prepared as a remedy for the ‘stone disease’ then sweeping through Europe, which was first announced in J. B. van Helmont's De lithiasi (1644)."

https://royalsocietypublishing.org/doi/1....2014.0010
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